C.F.R. » Title 21 » CHAPTER II—DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE › PART 1308—SCHEDULES OF CONTROLLED SUBSTANCES

21 C.F.R. § 1308.14

Schedule IV

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(a) Schedule IV shall consist of the drugs and other substances, by whatever official name, common or usual name, chemical name, or brand name designated, listed in this section. Each drug or substance has been assigned the DEA Controlled Substances Code Number set forth opposite it.

(b) Narcotic drugs. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation containing any of the following narcotic drugs, or their salts calculated as the free anhydrous base or alkaloid, in limited quantities as set forth below:

(1) Not more than 1 milligram of difenoxin and not less than 25 micrograms of atropine sulfate per dosage unit9167
(2) Dextropropoxyphene (alpha-(+)-4-dimethylamino-1,2-diphenyl-3-methyl-2-propionoxybutane)9278
(3) 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol, its salts, optical and geometric isomers and salts of these isomers (including tramadol)9752

(c) Depressants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances, including its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:

(1) Alfaxalone2731
(2) Alprazolam2882
(3) Barbital2145
(4) Brexanolone2400
(5) Bromazepam2748
(6) Camazepam2749
(7) Carisoprodol8192
(8) Chloral betaine2460
(9) Chloral hydrate2465
(10) Chlordiazepoxide2744
(11) Clobazam2751
(12) Clonazepam2737
(13) Clorazepate2768
(14) Clotiazepam2752
(15) Cloxazolam2753
(16) Daridorexant2410
(17) Delorazepam2754
(18) Diazepam2765
(19) Dichloralphenazone2467
(20) Estazolam2756
(21) Ethchlorvynol2540
(22) Ethinamate2545
(23) Ethyl loflazepate2758
(24) Fludiazepam2759
(25) Flunitrazepam2763
(26) Flurazepam2767
(27) Fospropofol2138
(28) Halazepam2762
(29) Haloxazolam2771
(30) Ketazolam2772
(31) Lemborexant2245
(32) Loprazolam2773
(33) Lorazepam2885
(34) Lormetazepam2774
(35) Mebutamate2800
(36) Medazepam2836
(37) Meprobamate2820
(38) Methohexital2264
(39) Methylphenobarbital (mephobarbital)2250
(40) Midazolam2884
(41) Nimetazepam2837
(42) Nitrazepam2834
(43) Nordiazepam2838
(44) Oxazepam2835
(45) Oxazolam2839
(46) Paraldehyde2585
(47) Petrichloral2591
(48) Phenobarbital2285
(49) Pinazepam2883
(50) Prazepam2764
(51) Quazepam2881
(52) Remimazolam2846
(53) Suvorexant2223
(54) Temazepam2925
(55) Tetrazepam2886
(56) Triazolam2887
(57) Zaleplon2781
(58) Zolpidem2783
(59) Zopiclone2784
(60) Zuranolone2420

(d) [Reserved]

(e) Lorcaserin. Any material, compound, mixture, or preparation which contains any quantity of the following substances, including its salts, isomers, and salts of such isomers, whenever the existence of such salts, isomers, and salts of isomers is possible:

(1) Lorcaserin1625

(f) Stimulants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system, including its salts, isomers and salts of isomers:

(1) Cathine ((+)-norpseudoephedrine)1230
(2) Diethylpropion1610
(3) Fencamfamin1760
(4) Fenproporex1575
(5) Mazindol1605
(6) Mefenorex1580
(7)Modafinil1680
(8) Pemoline (including organometallic complexes and chelates thereof)1530
(9) Phentermine1640
(10) Pipradrol1750
(11) Serdexmethylphenidate1729
(12) Sibutramine1675
(13) Solriamfetol (2-amino-3-phenylpropyl carbamate; benzenepropanol, beta-amino-, carbamate (ester))1650
(14) SPA ((-)-1-dimethylamino- 1,2-diphenylethane)1635

(g) Other substances. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture or preparation which contains any quantity of the following substances, including its salts:

(1) Pentazocine9709
(2) Butorphanol (including its optical isomers)9720
(3) Eluxadoline (5-[[[(2S)-2-amino-3-[4-aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl][(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino]methyl]-2-methoxybenzoic acid) (including its optical isomers) and its salts, isomers, and salts of isomers (9725).
[39 FR 22143, June 20, 1974] Editorial Note:For Federal Register citations affecting § 1308.14, see the List of CFR Sections Affected, which appears in the Finding Aids section of the printed volume and at www.govinfo.gov.
Notes of Decisions
Cited in 44 cases (7 in the last 5 years), 1978–2024 · leading case: Coronado v. Holder, 759 F.3d 977 (9th Cir. 2014).
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Coronado v. Holder, 759 F.3d 977 (9th Cir. 2014). · cites it 3× “13 Schedule IV (§ 11057) generally 21 C.F.R. § 1308.14 Schedule V(§ 11058) generally 21 C.”
United States v. Daahir Caseer, 399 F.3d 828 (6th Cir. 2005). · cites it 4× “Khat is legal in many parts of East Africa, the Middle East, and Europe; however, khat is illegal in the United States because it contains cathinone, a Schedule I controlled substance, and cathine, a Schedule IV controlled substance.”
Shariff David Bula Lopez v. U.S. Attorney Gen., 914 F.3d 1292 (11th Cir. 2019). · cites it 2× “§ 1308 "; and (3) "Flunitrazepam is listed at 21 C.F.R. § 1308.14 (c)(23) and is a controlled substance under schedule IV.”
Raul Quijada Coronado v. Eric Holder, Jr., 747 F.3d 662 (9th Cir. 2014). · cites it 3× “13 Schedule IV (§ 11057) generally 21 C.F.R. § 1308.14 Schedule V (§ 11058) generally 21 C.”
Yarbrough v. State, 405 So. 2d 721 (Ala. Crim. App. 1981). · cites it 2× “Appellant's only issue on appeal deals with the sufficiency of the State's evidence, raised by his motions to exclude the State's evidence and for a new trial. Both motions were general in nature stating no specific grounds.”
Wright v. State, 981 S.W.2d 197 (Tex. Crim. App. 1998). · cites it 2× “See 21 C.F.R. § 1308.14 . [6] We express no opinion as to whether the evidence at appellant's trial raised the "ultimate user" defense or whether the trial court should have instructed the jury on it.”
United States v. Otuonye, 995 F.3d 1191 (10th Cir. 2021). “21 C.F.R. § 1308.14 (c)(2). Title 21 U.S.”
People v. Turmon, 340 N.W.2d 620 (Mich. 1983). · cites it 2× “[6] 21 CFR 1308.14(f). The Board of Pharmacy promulgated *654 1979 AC, R 338.”
Oakey v. May Maple Pharmacy, Inc., 2017 NMCA 54 (N.M. Ct. App. 2017). “21 C.F.R. § 1308.14 (c)(2) (2015); § 30-31-5(D); 16.”
United States v. Nicholas Anthony Moccia, 681 F.2d 61 (1st Cir. 1982). “§§ 812 (Schedule I(c)(10)), 841; 21 C.F.R. § 1308.14 (e)(1) (1981). He was sentenced under the “Dangerous Special Drug Offender” statute, 21 U.”
United States v. Abdulle, 564 F.3d 119 (2d Cir. 2009). “See Schedules of Controlled Substances: Placement of Cathinone and 2,5-Dimethoxy-4-ethylampheta-mine Into Schedule I, 58 Fed.”
Roger G. Gousse v. John Ashcroft, Attorney Gen., 339 F.3d 91 (2d Cir. 2003). “1, 1997) (codified at 21 C.F.R. § 1308.14 (f)(2)). Gousse’s conviction was entered on August 13, 1998.”
Show all 44 citing cases →
— 21 C.F.R. § 1308.14(c) — 1 case
Grinstead, Teresa Lynn (Tex. Crim. App. 2022).
— 21 C.F.R. § 1308.14(f) — 1 case
People v. Turmon, 340 N.W.2d 620 (Mich. 1983). “[6] 21 CFR 1308.14(f). The Board of Pharmacy promulgated *654 1979 AC, R 338.”
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